Inhibition functions can be improved in children with autism spectrum disorders: An eye‐tracking study

Simona Caldani (1, 2) , Elise Humeau (2) , Richard Delorme (2) , Maria Pia Bucci (1, 2)

1 MoDyCo - Modèles, Dynamiques, Corpus
2 Hôpital Robert Debré Paris

Cognitive remediation therapy interventions could improve cognitive functioning in subjects with autism. To investigate the benefit of a short cognitive training rehabilitation in children with autism spectrum disorder (ASD) on pursuit and fixation performances. We recruited two groups (G1 and G2) of 30 children with ASD, sex-, IQ- and age-matched (mean 11.6 ± 0.5 years), and pursuit and fixation eye movements were recorded twice at T1 and T2. Between T1 and T2, a 10-min cognitive training was performed by the G1 group only, whereas the G2 group had a 10-min of rest. For all children with ASD enrolled in the study, there was a positive correlation between restricted and repetitive behaviour scores of both Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) and the number of saccades recorded during the fixation task at T1. At T1, oculomotor performances were similar for both groups of ASD children (G1 and G2). At T2, we observed a significant reduction in the number of saccades made during both pursuit and fixation tasks. Our findings underlined the importance to promote cognitive training rehabilitation for children with ASD, leading to a better performance in inhibitory and attention functioning responsible for pursuit and fixation eye movement's performance.

Keywords: autism spectrum disorder children eye movements inhibitory mechanism; autism spectrum disorder; children; eye movements; inhibitory mechanism

Domains: Neuroscience

Simona Caldani, Elise Humeau, Richard Delorme, Maria Pia Bucci. Inhibition functions can be improved in children with autism spectrum disorders: An eye‐tracking study. International Journal of Developmental Neuroscience, 2023, ⟨10.1002/jdn.10276⟩. ⟨hal-04109625⟩